What Moves Like PVLA

Palvella Therapeutics, Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track PVLA most closely over the past year, filtered to risk comparable with PVLA's own.

Closest match

VIR Vir Biotechnology, Inc. — 0.461 correlation over the past year, and 22% calmer than PVLA.

252 sessions to 2026-09-10 · PVLA volatility 83.4% annualised · $27.5M a day
Ticker 1-year correlation 3-year Volatility vs PVLA Risk What it is
VIR Vir Biotechnology, Inc.
0.461
0.199 0.78× 22% calmer Biological Products, (No Diagnostic Substances)
BEAM Beam Therapeutics Inc.
0.383
0.212 0.90× 10% calmer Biological Products, (No Diagnostic Substances)
EDIT Editas Medicine, Inc.
0.378
0.213 1.02× similar Biological Products, (No Diagnostic Substances)
CLDX Celldex Therapeutics, Inc.
0.377
0.223 0.61× 40% calmer In Vitro & In Vivo Diagnostic Substances
TRVI Trevi Therapeutics, Inc.
0.374
0.147 0.72× 28% calmer Pharmaceutical Preparations
ARQT Arcutis Biotherapeutics, Inc.
0.372
0.153 0.67× 33% calmer Pharmaceutical Preparations
DNTH Dianthus Therapeutics, Inc.
0.369
0.176 0.73× 27% calmer Pharmaceutical Preparations
VYGR Voyager Therapeutics, Inc.
0.367
0.203 0.71× 29% calmer Biological Products, (No Diagnostic Substances)
IMMX Immix Biopharma, Inc.
0.364
0.151 1.02× similar Pharmaceutical Preparations
ORIC Oric Pharmaceuticals, Inc.
0.362
0.203 1.03× similar Pharmaceutical Preparations
NRIX Nurix Therapeutics, Inc.
0.360
0.169 0.72× 28% calmer Pharmaceutical Preparations
RCUS Arcus Biosciences, Inc.
0.354
0.195 0.74× 26% calmer Pharmaceutical Preparations
MBOT Microbot Medical Inc.
0.349
0.163 0.86× 15% calmer Surgical & Medical Instruments & Apparatus
KURA Kura Oncology, Inc.
0.348
0.151 0.73× 27% calmer Pharmaceutical Preparations
LCTX Lineage Cell Therapeutics, Inc.
0.346
0.103 0.67× 33% calmer Biological Products, (No Diagnostic Substances)
XNCR Xencor, Inc.
0.331
0.237 0.81× 20% calmer Pharmaceutical Preparations
IMTX Immatics N.V.
0.330
0.187 0.74× 26% calmer Biological Products, (No Diagnostic Substances)
IOVA Iovance Biotherapeutics, Inc.
0.328
0.224 1.20× 20% choppier Biological Products, (No Diagnostic Substances)
SVRA Savara, Inc.
0.325
0.210 0.64× 36% calmer Pharmaceutical Preparations
FDMT 4D Molecular Therapeutics, Inc.
0.324
0.173 0.96× similar Biological Products, (No Diagnostic Substances)
CADL Candel Therapeutics, Inc.
0.321
0.105 0.87× 13% calmer Biological Products, (No Diagnostic Substances)
ABEO Abeona Therapeutics Inc.
0.321
0.111 0.65× 35% calmer Pharmaceutical Preparations
ABCL AbCellera Biologics Inc.
0.321
0.178 1.05× similar Pharmaceutical Preparations
SGMT Sagimet Biosciences Inc. - Series A
0.313
0.136 1.02× similar Pharmaceutical Preparations
VKTX Viking Therapeutics, Inc.
0.312
0.150 0.72× 29% calmer Pharmaceutical Preparations

Showing 25 of 29 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.