What Moves Like ZYME

Zymeworks Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track ZYME most closely over the past year, filtered to risk comparable with ZYME's own.

Closest match

JAZZ Jazz Pharmaceuticals plc — 0.533 correlation over the past year, and 31% calmer than ZYME.

251 sessions to 2026-09-10 · ZYME volatility 54.1% annualised · $13.5M a day
Ticker 1-year correlation 3-year Volatility vs ZYME Risk What it is
JAZZ Jazz Pharmaceuticals plc
0.533
0.388 0.69× 31% calmer Pharmaceutical Preparations
VSTM Verastem, Inc.
0.393
0.259 1.37× 37% choppier Pharmaceutical Preparations
VIR Vir Biotechnology, Inc.
0.360
0.313 1.21× 21% choppier Biological Products, (No Diagnostic Substances)
BBIO BridgeBio Pharma, Inc.
0.358
0.326 0.86× 14% calmer Pharmaceutical Preparations
IMNM Immunome, Inc.
0.350
0.374 1.26× 26% choppier Pharmaceutical Preparations
XNCR Xencor, Inc.
0.347
0.406 1.24× 24% choppier Pharmaceutical Preparations
ABUS Arbutus Biopharma Corporation
0.347
0.321 0.86× 14% calmer Pharmaceutical Preparations
DYN Dyne Therapeutics, Inc.
0.339
0.347 1.45× 45% choppier Pharmaceutical Preparations
ANNX Annexon, Inc.
0.336
0.347 1.44× 44% choppier Pharmaceutical Preparations
PTGX Protagonist Therapeutics, Inc.
0.336
0.274 0.93× similar Pharmaceutical Preparations
VERA Vera Therapeutics, Inc.
0.332
0.248 1.10× similar Pharmaceutical Preparations
IDYA IDEAYA Biosciences, Inc.
0.326
0.357 0.84× 16% calmer Pharmaceutical Preparations
VYGR Voyager Therapeutics, Inc.
0.325
0.350 1.09× similar Biological Products, (No Diagnostic Substances)
PCVX Vaxcyte, Inc.
0.325
0.311 0.85× 15% calmer Biological Products, (No Diagnostic Substances)
JANX Janux Therapeutics, Inc.
0.323
0.265 1.37× 37% choppier Pharmaceutical Preparations
DMAC DiaMedica Therapeutics Inc.
0.323
0.264 1.02× similar Pharmaceutical Preparations
SNDX Syndax Pharmaceuticals, Inc.
0.320
0.365 0.95× similar Pharmaceutical Preparations
PHVS Pharvaris N.V.
0.315
0.200 1.00× similar Pharmaceutical Preparations
MIST Milestone Pharmaceuticals Inc.
0.306
0.221 1.34× 34% choppier Pharmaceutical Preparations
TARS Tarsus Pharmaceuticals, Inc.
0.305
0.276 0.86× 14% calmer Biological Products, (No Diagnostic Substances)
TNXP Tonix Pharmaceuticals Holding Corp.
0.305
0.128 1.34× 34% choppier Pharmaceutical Preparations
MDGL Madrigal Pharmaceuticals, Inc.
0.303
0.274 0.81× 19% calmer Pharmaceutical Preparations
MLYS Mineralys Therapeutics, Inc.
0.301
0.172 1.10× similar Pharmaceutical Preparations

Showing 23 of 23 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.