What Moves Like DNA

Ginkgo Bioworks Holdings, Inc. Class A Biological Products, (No Diagnostic Substances) · NYSE

The tradable tickers whose daily moves track DNA most closely over the past year, filtered to risk comparable with DNA's own.

Closest match

TWST Twist Bioscience Corporation — 0.639 correlation over the past year, and 19% calmer than DNA.

About DNA

Annualised volatility 103.1%
Beta vs SPY 3.35
Market correlation 0.444
Traded per day $11.6M
Rate sensitivity -0.10
Volatility sensitivity -0.45

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Revenue $170.2M
Operating income -$315.3M
Net income -$312.8M
Diluted EPS $-5.64
Total assets $1.03B
Total liabilities $589.9M
Shareholders' equity $443.2M
Cash & equivalents $143.9M
Shares outstanding 61.7M
251 sessions to 2026-11-09 · DNA volatility 103.1% annualised · $11.6M a day
Ticker 1-year correlation 3-year Volatility vs DNA Risk What it is
TWST Twist Bioscience Corporation
0.639
0.557 0.81× 19% calmer Biological Products, (No Diagnostic Substances)
RXRX Recursion Pharmaceuticals, Inc.
0.636
0.532 0.72× 28% calmer Biological Products, (No Diagnostic Substances)
PACB Pacific Biosciences of California, Inc.
0.579
0.498 0.91× similar Laboratory Analytical Instruments
SDGR Schrodinger, Inc.
0.567
0.498 0.65× 35% calmer Pharmaceutical Preparations
TEM Tempus AI, Inc.
0.547
— 0.74× 26% calmer Services-Computer Programming, Data Processing, Etc.
SERV Serve Robotics Inc.
0.534
— 0.87× 13% calmer General Industrial Machinery & Equipment, Nec
ABSI Absci Corporation
0.533
0.482 1.03× similar Services-Commercial Physical & Biological Research
TXG 10x Genomics, Inc.
0.520
0.464 0.74× 26% calmer Laboratory Analytical Instruments
NTLA Intellia Therapeutics, Inc.
0.511
0.482 0.74× 26% calmer In Vitro & In Vivo Diagnostic Substances
NVAX Novavax, Inc.
0.497
0.246 0.71× 30% calmer Biological Products, (No Diagnostic Substances)
EBS Emergent BioSolutions Inc.
0.496
0.253 0.67× 33% calmer Pharmaceutical Preparations
FLGT Fulgent Genetics, Inc.
0.494
0.351 0.63× 37% calmer Services-Medical Laboratories
QSI Quantum-Si Incorporated
0.478
0.340 0.98× similar Measuring & Controlling Devices, Nec
SANA Sana Biotechnology, Inc.
0.476
0.318 0.73× 27% calmer Biological Products, (No Diagnostic Substances)
GRAL GRAIL, Inc.
0.466
— 1.00× similar Services-Medical Laboratories
UPST Upstart Holdings, Inc.
0.466
0.342 0.63× 37% calmer Finance Services
ARCT Arcturus Therapeutics Holdings Inc.
0.466
0.363 0.80× 20% calmer Pharmaceutical Preparations
ENVX Enovix Corporation
0.465
0.363 0.88× 12% calmer Miscellaneous Electrical Machinery, Equipment & Supplies
QBTS D-Wave Quantum Inc.
0.459
0.323 1.01× similar Services-Computer Processing & Data Preparation
RGTI Rigetti Computing, Inc.
0.456
0.366 0.94× similar Services-Computer Programming Services
BEAM Beam Therapeutics Inc.
0.454
0.461 0.70× 30% calmer Biological Products, (No Diagnostic Substances)
BULZ MicroSectors FANG & Innovation 3x Leveraged ETN
0.451
0.380 0.91× similar Fund
LTBR Lightbridge Corporation
0.449
0.255 0.79× 21% calmer Industrial Inorganic Chemicals
DAPP VanEck Digital Transformation ETF
0.448
0.403 0.64× 36% calmer Fund
LAES SEALSQ Corp
0.448
0.167 0.81× 19% calmer Semiconductors & Related Devices

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.