What Moves Like LGND

Ligand Pharmaceuticals Incorporated Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track LGND most closely over the past year, filtered to risk comparable with LGND's own.

Closest match

PTH Invesco Dorsey Wright Healthcare Momentum ETF — 0.519 correlation over the past year, and 22% calmer than LGND.

About LGND

Annualised volatility 36.6%
Beta vs SPY 0.90
Market correlation 0.335
Traded per day $73.9M
Rate sensitivity -0.18
Volatility sensitivity -0.32

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Revenue $268.1M
Operating income $41.0M
Net income $124.5M
Diluted EPS $6.13
Total assets $1.53B
Total liabilities $534.8M
Shareholders' equity $997.3M
Cash & equivalents $115.1M
Shares outstanding 20.0M
251 sessions to 2026-11-09 · LGND volatility 36.6% annualised · $73.9M a day
Ticker 1-year correlation 3-year Volatility vs LGND Risk What it is
PTH Invesco Dorsey Wright Healthcare Momentum ETF
0.519
0.497 0.78× 22% calmer Fund
XBI State Street SPDR S&P Biotech ETF
0.500
0.504 0.83× 17% calmer Fund
HQH abrdn Healthcare Investors Shares of Beneficial Interest
0.493
0.386 0.65× 35% calmer —
XPH State Street SPDR S&P Pharmaceuticals ETF
0.483
0.460 0.67× 33% calmer Fund
IBBQ Invesco Nasdaq Biotechnology ETF
0.475
0.467 0.64× 36% calmer Fund
HQL abrdn Life Sciences Investors Shares of Beneficial Interest
0.460
0.385 0.67× 33% calmer —
IBB iShares Biotechnology ETF
0.459
0.456 0.65× 35% calmer Fund
GNOM Global X Genomics & Biotechnology ETF
0.454
0.456 0.97× similar Fund
BBP Virtus Biotech ETF
0.454
0.490 0.74× 26% calmer Fund
IDNA iShares Genomics Immunology and Healthcare ETF
0.449
0.457 0.85× 15% calmer Fund
VTWG Vanguard Russell 2000 Growth ETF
0.448
0.465 0.63× 37% calmer Fund
IWO iShares Russell 2000 Growth Fund
0.444
0.467 0.62× 38% calmer Fund
FBT First Trust Amex Biotech Index Fund
0.443
0.420 0.62× 38% calmer Fund
SBIO ALPS Medical Breakthroughs ETF
0.439
0.488 0.92× similar Fund
JSML Janus Henderson Small Cap Growth Alpha ETF
0.437
0.422 0.61× 39% calmer Fund
IWC iShares Microcap ETF
0.436
0.456 0.65× 35% calmer Fund
ARKG ARK Genomic Revolution ETF
0.436
0.424 1.30× 30% choppier Fund
JSMD Janus Henderson Small/Mid Cap Growth Alpha ETF
0.431
0.423 0.63× 37% calmer Fund
VFMO Vanguard U.S. Momentum Factor ETF
0.418
0.426 0.69× 31% calmer Fund
CSMD Congress SMid Growth ETF
0.403
0.406 0.61× 40% calmer Fund
KOMP State Street SPDR S&P Kensho New Economies Composite ETF
0.382
0.408 0.74× 26% calmer Fund
ARKK ARK Innovation ETF
0.379
0.401 1.05× similar Fund
COGT Cogent Biosciences, Inc.
0.376
0.237 1.26× 26% choppier Pharmaceutical Preparations
ARQT Arcutis Biotherapeutics, Inc.
0.375
0.302 1.54× 54% choppier Pharmaceutical Preparations
PTGX Protagonist Therapeutics, Inc.
0.373
0.197 1.10× similar Pharmaceutical Preparations

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.