What Moves Like TYRA

Tyra Biosciences, Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track TYRA most closely over the past year, filtered to risk comparable with TYRA's own.

Closest match

CGEM Cullinan Therapeutics, Inc. — 0.371 correlation over the past year, and 19% choppier than TYRA.

About TYRA

Annualised volatility 66.3%
Beta vs SPY 0.63
Market correlation 0.121
Traded per day $21.6M
Rate sensitivity 0.02
Volatility sensitivity -0.12

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Operating income -$132.8M
Net income -$119.9M
Diluted EPS $-2.01
Total assets $412.0M
Total liabilities $24.5M
Shareholders' equity $387.6M
Cash & equivalents $85.0M
Shares outstanding 59.5M
252 sessions to 2026-09-10 · TYRA volatility 66.3% annualised · $21.6M a day
Ticker 1-year correlation 3-year Volatility vs TYRA Risk What it is
CGEM Cullinan Therapeutics, Inc.
0.371
0.296 1.19× 19% choppier Biological Products, (No Diagnostic Substances)
RCUS Arcus Biosciences, Inc.
0.364
0.328 0.93× similar Pharmaceutical Preparations
NRIX Nurix Therapeutics, Inc.
0.350
0.348 0.91× similar Pharmaceutical Preparations
ZURA Zura Bio Limited - Class A Ordinary shares
0.333
0.247 1.46× 46% choppier Biological Products, (No Diagnostic Substances)
RLAY Relay Therapeutics, Inc.
0.329
0.314 1.04× similar Biological Products, (No Diagnostic Substances)
XNCR Xencor, Inc.
0.325
0.337 1.01× similar Pharmaceutical Preparations
VKTX Viking Therapeutics, Inc.
0.325
0.219 0.90× 10% calmer Pharmaceutical Preparations
PCVX Vaxcyte, Inc.
0.325
0.271 0.69× 31% calmer Biological Products, (No Diagnostic Substances)
IDYA IDEAYA Biosciences, Inc.
0.320
0.312 0.69× 31% calmer Pharmaceutical Preparations
AURA Aura Biosciences, Inc.
0.310
0.349 0.87× 13% calmer Biological Products, (No Diagnostic Substances)
VIR Vir Biotechnology, Inc.
0.306
0.261 0.98× similar Biological Products, (No Diagnostic Substances)
CLDX Celldex Therapeutics, Inc.
0.305
0.289 0.76× 24% calmer In Vitro & In Vivo Diagnostic Substances
RXRX Recursion Pharmaceuticals, Inc.
0.305
0.307 1.09× similar Biological Products, (No Diagnostic Substances)
PACS PACS Group, Inc.
0.302
1.47× 47% choppier Services-Skilled Nursing Care Facilities
EDIT Editas Medicine, Inc.
0.301
0.275 1.28× 28% choppier Biological Products, (No Diagnostic Substances)
MIRM Mirum Pharmaceuticals, Inc.
0.301
0.209 0.69× 31% calmer Pharmaceutical Preparations
KYMR Kymera Therapeutics, Inc.
0.301
0.353 0.96× similar Biological Products, (No Diagnostic Substances)

Showing 17 of 17 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.