What Moves Like DSGN

Design Therapeutics, Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track DSGN most closely over the past year, filtered to risk comparable with DSGN's own.

Closest match

DYN Dyne Therapeutics, Inc. — 0.406 correlation over the past year, and about as volatile as DSGN.

About DSGN

Annualised volatility 75.1%
Beta vs SPY 1.19
Market correlation 0.205
Traded per day $8.0M
Rate sensitivity -0.09
Volatility sensitivity -0.17

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Operating income -$79.5M
Net income -$69.8M
Diluted EPS $-1.22
Total assets $230.4M
Total liabilities $12.4M
Shareholders' equity $218.1M
Cash & equivalents $12.8M
Shares outstanding 62.4M
252 sessions to 2026-09-30 · DSGN volatility 75.1% annualised · $8.0M a day
Ticker 1-year correlation 3-year Volatility vs DSGN Risk What it is
DYN Dyne Therapeutics, Inc.
0.406
0.356 1.04× similar Pharmaceutical Preparations
RCKT Rocket Pharmaceuticals, Inc.
0.399
0.329 0.96× similar Pharmaceutical Preparations
FDMT 4D Molecular Therapeutics, Inc.
0.399
0.261 1.05× similar Biological Products, (No Diagnostic Substances)
SLDB Solid Biosciences Inc.
0.382
0.307 1.05× similar Biological Products, (No Diagnostic Substances)
SYRE Spyre Therapeutics, Inc.
0.377
0.305 0.92× similar Pharmaceutical Preparations
ENTA Enanta Pharmaceuticals, Inc.
0.359
0.221 0.67× 33% calmer Pharmaceutical Preparations
IFRX InflaRx N.V.
0.358
0.203 1.31× 31% choppier Pharmaceutical Preparations
KURA Kura Oncology, Inc.
0.358
0.275 0.79× 21% calmer Pharmaceutical Preparations
DRUG Bright Minds Biosciences Inc.
0.358
0.137 0.86× 14% calmer Pharmaceutical Preparations
RGNX REGENXBIO Inc.
0.358
0.347 1.25× 25% choppier Biological Products, (No Diagnostic Substances)
SIMO Silicon Motion Technology Corporation
0.353
0.233 1.14× 14% choppier Semiconductors & Related Devices
PHVS Pharvaris N.V.
0.352
0.224 0.73× 27% calmer Pharmaceutical Preparations
MIRM Mirum Pharmaceuticals, Inc.
0.345
0.241 0.62× 38% calmer Pharmaceutical Preparations
SRRK Scholar Rock Holding Corporation
0.345
0.200 0.79× 21% calmer Biological Products, (No Diagnostic Substances)
IMVT Immunovant, Inc.
0.342
0.312 0.79× 21% calmer Biological Products, (No Diagnostic Substances)
KYTX Kyverna Therapeutics, Inc.
0.341
— 1.29× 29% choppier Biological Products, (No Diagnostic Substances)
VIR Vir Biotechnology, Inc.
0.337
0.233 0.86× 14% calmer Biological Products, (No Diagnostic Substances)
IMNM Immunome, Inc.
0.337
0.296 0.86× 14% calmer Pharmaceutical Preparations
LXEO Lexeo Therapeutics, Inc.
0.336
— 1.01× similar Biological Products, (No Diagnostic Substances)
IMRX Immuneering Corporation
0.333
0.189 1.09× similar Pharmaceutical Preparations
VYGR Voyager Therapeutics, Inc.
0.332
0.314 0.77× 23% calmer Biological Products, (No Diagnostic Substances)
AVTX Avalo Therapeutics, Inc.
0.325
0.189 1.09× similar Pharmaceutical Preparations
BBIO BridgeBio Pharma, Inc.
0.324
0.244 0.63× 37% calmer Pharmaceutical Preparations
IMTX Immatics N.V.
0.323
0.280 0.79× 21% calmer Biological Products, (No Diagnostic Substances)
AVBP ArriVent BioPharma, Inc.
0.318
— 0.76× 24% calmer Pharmaceutical Preparations

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.