What Moves Like TSHA

Taysha Gene Therapies, Inc. Biological Products, (No Diagnostic Substances) · Nasdaq

The tradable tickers whose daily moves track TSHA most closely over the past year, filtered to risk comparable with TSHA's own.

Closest match

NGNE Neurogene Inc. — 0.463 correlation over the past year, and about as volatile as TSHA.

About TSHA

Annualised volatility 89.9%
Beta vs SPY 1.78
Market correlation 0.255
Traded per day $14.2M

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Revenue $9.8M
Operating income -$110.5M
Net income -$109.0M
Diluted EPS $-0.34
Total assets $300.4M
Total liabilities $88.4M
Shareholders' equity $211.9M
Cash & equivalents $276.6M
Shares outstanding 287.3M
252 sessions to 2026-09-10 · TSHA volatility 89.9% annualised · $14.2M a day
Ticker 1-year correlation 3-year Volatility vs TSHA Risk What it is
NGNE Neurogene Inc.
0.463
0.228 0.92× similar Pharmaceutical Preparations
PRME Prime Medicine, Inc.
0.458
0.330 0.99× similar Biological Products, (No Diagnostic Substances)
STOK Stoke Therapeutics, Inc.
0.420
0.285 0.65× 35% calmer Pharmaceutical Preparations
EDIT Editas Medicine, Inc.
0.405
0.287 0.94× similar Biological Products, (No Diagnostic Substances)
MGTX MeiraGTx Holdings plc
0.404
0.328 0.67× 33% calmer Biological Products, (No Diagnostic Substances)
CRSP CRISPR Therapeutics AG
0.404
0.294 0.67× 33% calmer Biological Products, (No Diagnostic Substances)
ABEO Abeona Therapeutics Inc.
0.401
0.235 0.60× 40% calmer Pharmaceutical Preparations
RGNX REGENXBIO Inc.
0.394
0.290 1.04× similar Biological Products, (No Diagnostic Substances)
SANA Sana Biotechnology, Inc.
0.393
0.254 0.95× similar Biological Products, (No Diagnostic Substances)
CRBU Caribou Biosciences, Inc.
0.389
0.253 0.82× 18% calmer Biological Products, (No Diagnostic Substances)
SLDB Solid Biosciences Inc.
0.388
0.310 0.89× 11% calmer Biological Products, (No Diagnostic Substances)
RXRX Recursion Pharmaceuticals, Inc.
0.384
0.291 0.80× 20% calmer Biological Products, (No Diagnostic Substances)
AVBP ArriVent BioPharma, Inc.
0.377
0.65× 35% calmer Pharmaceutical Preparations
DNLI Denali Therapeutics Inc.
0.374
0.287 0.63× 37% calmer Biological Products, (No Diagnostic Substances)
SRPT Sarepta Therapeutics, Inc.
0.372
0.242 0.90× similar Pharmaceutical Preparations
LXEO Lexeo Therapeutics, Inc.
0.372
0.86× 14% calmer Biological Products, (No Diagnostic Substances)
RCKT Rocket Pharmaceuticals, Inc.
0.368
0.287 0.80× 21% calmer Pharmaceutical Preparations
VIR Vir Biotechnology, Inc.
0.368
0.212 0.72× 28% calmer Biological Products, (No Diagnostic Substances)
QBTS D-Wave Quantum Inc.
0.367
0.177 1.25× 25% choppier Services-Computer Processing & Data Preparation
ARQQ Arqit Quantum Inc.
0.364
0.178 1.30× 30% choppier Services-Prepackaged Software
FDMT 4D Molecular Therapeutics, Inc.
0.364
0.254 0.89× 11% calmer Biological Products, (No Diagnostic Substances)
BEAM Beam Therapeutics Inc.
0.358
0.310 0.83× 17% calmer Biological Products, (No Diagnostic Substances)
RGTI Rigetti Computing, Inc.
0.358
0.206 1.19× 19% choppier Services-Computer Programming Services
MIST Milestone Pharmaceuticals Inc.
0.358
0.150 0.81× 19% calmer Pharmaceutical Preparations
TRVI Trevi Therapeutics, Inc.
0.356
0.190 0.67× 34% calmer Pharmaceutical Preparations

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.