What Moves Like IOVA

Iovance Biotherapeutics, Inc. Biological Products, (No Diagnostic Substances) · Nasdaq

The tradable tickers whose daily moves track IOVA most closely over the past year, filtered to risk comparable with IOVA's own.

Closest match

VIR Vir Biotechnology, Inc. — 0.388 correlation over the past year, and 38% calmer than IOVA.

About IOVA

Annualised volatility 104.4%
Beta vs SPY 1.22
Market correlation 0.151
Traded per day $59.8M
Rate sensitivity -0.12
Volatility sensitivity -0.16

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Revenue $263.5M
Operating income -$403.4M
Net income -$391.0M
Diluted EPS $-1.09
Total assets $925.7M
Total liabilities $203.9M
Shareholders' equity $721.8M
Cash & equivalents $196.5M
Shares outstanding 438.1M
252 sessions to 2026-09-30 · IOVA volatility 104.4% annualised · $59.8M a day
Ticker 1-year correlation 3-year Volatility vs IOVA Risk What it is
VIR Vir Biotechnology, Inc.
0.388
0.332 0.62× 38% calmer Biological Products, (No Diagnostic Substances)
CRBU Caribou Biosciences, Inc.
0.365
0.397 0.66× 35% calmer Biological Products, (No Diagnostic Substances)
EDIT Editas Medicine, Inc.
0.346
0.333 0.79× 21% calmer Biological Products, (No Diagnostic Substances)
RXRX Recursion Pharmaceuticals, Inc.
0.345
0.359 0.71× 29% calmer Biological Products, (No Diagnostic Substances)
NKTX Nkarta, Inc.
0.342
0.281 0.72× 28% calmer Pharmaceutical Preparations
EOLS Evolus, Inc.
0.334
0.280 0.64× 36% calmer Pharmaceutical Preparations
AUTL Autolus Therapeutics plc
0.331
0.293 0.74× 26% calmer Biological Products, (No Diagnostic Substances)
ABCL AbCellera Biologics Inc.
0.322
0.318 0.84× 17% calmer Pharmaceutical Preparations
CLYM Climb Bio, Inc.
0.320
0.198 0.93× similar Pharmaceutical Preparations
ALEC Alector, Inc.
0.316
0.254 0.91× similar —
PROK ProKidney Corp. - Class A Ordinary Shares
0.314
0.194 0.70× 31% calmer Biological Products, (No Diagnostic Substances)
BEAM Beam Therapeutics Inc.
0.314
0.378 0.70× 30% calmer Biological Products, (No Diagnostic Substances)
LXEO Lexeo Therapeutics, Inc.
0.309
— 0.72× 28% calmer Biological Products, (No Diagnostic Substances)
PVLA Palvella Therapeutics, Inc.
0.306
0.224 0.80× 20% calmer Pharmaceutical Preparations
PRME Prime Medicine, Inc.
0.303
0.306 0.84× 16% calmer Biological Products, (No Diagnostic Substances)

Showing 15 of 15 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.