What Moves Like ORKA

Oruka Therapeutics, Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track ORKA most closely over the past year, filtered to risk comparable with ORKA's own.

Closest match

SYRE Spyre Therapeutics, Inc. — 0.465 correlation over the past year, and about as volatile as ORKA.

About ORKA

Annualised volatility 75.8%
Beta vs SPY 1.49
Market correlation 0.253
Traded per day $78.8M

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Operating income -$122.1M
Net income -$105.4M
Total assets $504.5M
Total liabilities $17.8M
Shareholders' equity $486.7M
Cash & equivalents $49.5M
Shares outstanding 50.2M
252 sessions to 2026-09-10 · ORKA volatility 75.8% annualised · $78.8M a day
Ticker 1-year correlation 3-year Volatility vs ORKA Risk What it is
SYRE Spyre Therapeutics, Inc.
0.465
0.291 0.92× similar Pharmaceutical Preparations
ENTA Enanta Pharmaceuticals, Inc.
0.427
0.266 1.23× 23% choppier Pharmaceutical Preparations
CGON CG Oncology, Inc.
0.407
0.75× 26% calmer Biological Products, (No Diagnostic Substances)
DNTH Dianthus Therapeutics, Inc.
0.402
0.192 0.81× 20% calmer Pharmaceutical Preparations
TRVI Trevi Therapeutics, Inc.
0.379
0.145 0.79× 21% calmer Pharmaceutical Preparations
VKTX Viking Therapeutics, Inc.
0.366
0.212 0.79× 21% calmer Pharmaceutical Preparations
XNCR Xencor, Inc.
0.361
0.287 0.89× 12% calmer Pharmaceutical Preparations
IMVT Immunovant, Inc.
0.352
0.207 0.79× 21% calmer Biological Products, (No Diagnostic Substances)
AVTX Avalo Therapeutics, Inc.
0.350
0.131 1.14× 14% choppier Pharmaceutical Preparations
MIRM Mirum Pharmaceuticals, Inc.
0.349
0.152 0.60× 40% calmer Pharmaceutical Preparations
ABSI Absci Corporation
0.343
0.223 1.40× 40% choppier Services-Commercial Physical & Biological Research
FDMT 4D Molecular Therapeutics, Inc.
0.340
0.210 1.06× similar Biological Products, (No Diagnostic Substances)
BEAM Beam Therapeutics Inc.
0.338
0.230 0.99× similar Biological Products, (No Diagnostic Substances)
NRIX Nurix Therapeutics, Inc.
0.336
0.225 0.79× 21% calmer Pharmaceutical Preparations
AVBP ArriVent BioPharma, Inc.
0.334
0.77× 23% calmer Pharmaceutical Preparations
WGMI CoinShares Bitcoin Mining and Digital Power ETF
0.330
0.230 1.11× 11% choppier Fund
DNLI Denali Therapeutics Inc.
0.329
0.233 0.74× 26% calmer Biological Products, (No Diagnostic Substances)
BKCH Global X Blockchain ETF
0.329
0.230 0.98× similar Fund
VIR Vir Biotechnology, Inc.
0.328
0.212 0.86× 14% calmer Biological Products, (No Diagnostic Substances)
KYMR Kymera Therapeutics, Inc.
0.327
0.235 0.84× 16% calmer Biological Products, (No Diagnostic Substances)
ADPT Adaptive Biotechnologies Corporation
0.324
0.116 0.91× similar Biological Products, (No Diagnostic Substances)
MARA MARA Holdings, Inc.
0.322
0.221 1.15× 15% choppier Finance Services
RFIL RF Industries, Ltd.
0.320
0.146 1.20× 20% choppier Electronic Connectors
FDIG Fidelity Crypto Industry and Digital Payments ETF
0.319
0.232 0.68× 32% calmer Fund
PCVX Vaxcyte, Inc.
0.318
0.223 0.61× 39% calmer Biological Products, (No Diagnostic Substances)

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.