What Moves Like ORKA

Oruka Therapeutics, Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track ORKA most closely over the past year, filtered to risk comparable with ORKA's own.

Closest match

SYRE Spyre Therapeutics, Inc. — 0.518 correlation over the past year, and about as volatile as ORKA.

About ORKA

Annualised volatility 69.5%
Beta vs SPY 1.41
Market correlation 0.263
Traded per day $75.6M
Rate sensitivity -0.19
Volatility sensitivity -0.33

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Operating income -$122.1M
Net income -$105.4M
Total assets $504.5M
Total liabilities $17.8M
Shareholders' equity $486.7M
Cash & equivalents $49.5M
Shares outstanding 50.2M
252 sessions to 2026-09-30 · ORKA volatility 69.5% annualised · $75.6M a day
Ticker 1-year correlation 3-year Volatility vs ORKA Risk What it is
SYRE Spyre Therapeutics, Inc.
0.518
0.297 0.99× similar Pharmaceutical Preparations
CGON CG Oncology, Inc.
0.419
— 0.82× 18% calmer Biological Products, (No Diagnostic Substances)
XNCR Xencor, Inc.
0.403
0.288 0.95× similar Pharmaceutical Preparations
DNTH Dianthus Therapeutics, Inc.
0.388
0.198 0.87× 13% calmer Pharmaceutical Preparations
MIRM Mirum Pharmaceuticals, Inc.
0.386
0.154 0.67× 33% calmer Pharmaceutical Preparations
TRVI Trevi Therapeutics, Inc.
0.385
0.149 0.83× 18% calmer Pharmaceutical Preparations
IMVT Immunovant, Inc.
0.383
0.270 0.86× 14% calmer Biological Products, (No Diagnostic Substances)
SGMT Sagimet Biosciences Inc. - Series A
0.372
0.209 1.24× 24% choppier Pharmaceutical Preparations
FDMT 4D Molecular Therapeutics, Inc.
0.371
0.212 1.13× 13% choppier Biological Products, (No Diagnostic Substances)
ANAB AnaptysBio, Inc.
0.358
0.196 0.90× similar Pharmaceutical Preparations
IMTX Immatics N.V.
0.356
0.237 0.86× 15% calmer Biological Products, (No Diagnostic Substances)
BEAM Beam Therapeutics Inc.
0.355
0.232 1.06× similar Biological Products, (No Diagnostic Substances)
VIR Vir Biotechnology, Inc.
0.350
0.215 0.93× similar Biological Products, (No Diagnostic Substances)
DRUG Bright Minds Biosciences Inc.
0.349
0.098 0.92× similar Pharmaceutical Preparations
AVBP ArriVent BioPharma, Inc.
0.345
— 0.82× 18% calmer Pharmaceutical Preparations
NRIX Nurix Therapeutics, Inc.
0.343
0.228 0.85× 15% calmer Pharmaceutical Preparations
KURA Kura Oncology, Inc.
0.342
0.223 0.85× 15% calmer Pharmaceutical Preparations
KYMR Kymera Therapeutics, Inc.
0.342
0.239 0.90× similar Biological Products, (No Diagnostic Substances)
ABSI Absci Corporation
0.340
0.224 1.53× 53% choppier Services-Commercial Physical & Biological Research
VKTX Viking Therapeutics, Inc.
0.338
0.211 1.00× similar Pharmaceutical Preparations
SVCO Silvaco Group, Inc.
0.337
— 1.35× 35% choppier —
ANNX Annexon, Inc.
0.337
0.172 1.07× similar Pharmaceutical Preparations
RFIL RF Industries, Ltd.
0.336
0.147 1.28× 28% choppier Electronic Connectors
AXSM Axsome Therapeutics, Inc.
0.333
0.177 0.63× 37% calmer Pharmaceutical Preparations
ARKG ARK Genomic Revolution ETF
0.331
0.265 0.65× 35% calmer Fund

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.