What Moves Like IRON

Disc Medicine, Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track IRON most closely over the past year, filtered to risk comparable with IRON's own.

Closest match

ARQT Arcutis Biotherapeutics, Inc. — 0.437 correlation over the past year, and 11% calmer than IRON.

About IRON

Annualised volatility 63.3%
Beta vs SPY 0.92
Market correlation 0.200
Traded per day $37.8M
Rate sensitivity -0.16
Volatility sensitivity -0.23

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Operating income -$236.0M
Net income -$212.2M
Diluted EPS $-6.01
Total assets $750.2M
Total liabilities $61.8M
Shareholders' equity $688.4M
Cash & equivalents $88.9M
Shares outstanding 38.2M
251 sessions to 2026-11-09 · IRON volatility 63.3% annualised · $37.8M a day
Ticker 1-year correlation 3-year Volatility vs IRON Risk What it is
ARQT Arcutis Biotherapeutics, Inc.
0.437
0.263 0.89× 11% calmer Pharmaceutical Preparations
ANNX Annexon, Inc.
0.412
0.283 1.19× 19% choppier Pharmaceutical Preparations
DYN Dyne Therapeutics, Inc.
0.377
0.305 1.01× similar Pharmaceutical Preparations
VYGR Voyager Therapeutics, Inc.
0.365
0.224 0.97× similar Biological Products, (No Diagnostic Substances)
PTGX Protagonist Therapeutics, Inc.
0.350
0.226 0.63× 37% calmer Pharmaceutical Preparations
CLDX Celldex Therapeutics, Inc.
0.349
0.277 0.83× 17% calmer In Vitro & In Vivo Diagnostic Substances
PRME Prime Medicine, Inc.
0.347
0.255 1.46× 46% choppier Biological Products, (No Diagnostic Substances)
LXEO Lexeo Therapeutics, Inc.
0.345
0.245 1.13× 13% choppier Biological Products, (No Diagnostic Substances)
TSHA Taysha Gene Therapies, Inc.
0.338
0.173 1.14× 14% choppier Biological Products, (No Diagnostic Substances)
SVRA Savara, Inc.
0.335
0.269 0.88× 12% calmer Pharmaceutical Preparations
IMMX Immix Biopharma, Inc.
0.323
0.209 1.33× 33% choppier Pharmaceutical Preparations
TVTX Travere Therapeutics, Inc.
0.323
0.254 0.99× similar Pharmaceutical Preparations
XNCR Xencor, Inc.
0.320
0.312 1.04× similar Pharmaceutical Preparations
EDIT Editas Medicine, Inc.
0.320
0.223 1.31× 31% choppier Biological Products, (No Diagnostic Substances)
DNLI Denali Therapeutics Inc.
0.317
0.271 0.88× 12% calmer Biological Products, (No Diagnostic Substances)
VIR Vir Biotechnology, Inc.
0.314
0.260 1.04× similar Biological Products, (No Diagnostic Substances)
RCUS Arcus Biosciences, Inc.
0.314
0.274 0.99× similar Pharmaceutical Preparations
FDMT 4D Molecular Therapeutics, Inc.
0.310
0.248 1.22× 22% choppier Biological Products, (No Diagnostic Substances)
PTCT PTC Therapeutics, Inc.
0.304
0.256 0.68× 32% calmer Pharmaceutical Preparations
CLF Cleveland-Cliffs Inc.
0.303
0.189 1.05× similar Metal Mining
KYTX Kyverna Therapeutics, Inc.
0.302
— 1.39× 39% choppier Biological Products, (No Diagnostic Substances)
CGEM Cullinan Therapeutics, Inc.
0.302
0.208 1.30× 30% choppier Biological Products, (No Diagnostic Substances)
ARKG ARK Genomic Revolution ETF
0.302
0.310 0.75× 25% calmer Fund
BNTC Benitec Biopharma Inc.
0.302
0.184 0.91× similar Pharmaceutical Preparations
AKBA Akebia Therapeutics, Inc.
0.302
0.264 1.41× 41% choppier Pharmaceutical Preparations

Showing 25 of 25 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.