What Moves Like LYEL

Lyell Immunopharma, Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track LYEL most closely over the past year, filtered to risk comparable with LYEL's own.

Closest match

TSHA Taysha Gene Therapies, Inc. — 0.426 correlation over the past year, and 22% calmer than LYEL.

About LYEL

Annualised volatility 91.4%
Beta vs SPY 1.75
Market correlation 0.261
Traded per day $1.7M
Rate sensitivity -0.20
Volatility sensitivity -0.26

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Revenue $36,000
Operating income -$269.4M
Net income -$274.4M
Diluted EPS $-16.06
Total assets $350.6M
Total liabilities $77.0M
Shareholders' equity $273.7M
Cash & equivalents $90.8M
Shares outstanding 23.3M
251 sessions to 2026-11-09 · LYEL volatility 91.4% annualised · $1.7M a day
Ticker 1-year correlation 3-year Volatility vs LYEL Risk What it is
TSHA Taysha Gene Therapies, Inc.
0.426
0.259 0.79× 22% calmer Biological Products, (No Diagnostic Substances)
SLDB Solid Biosciences Inc.
0.423
0.244 0.84× 16% calmer Biological Products, (No Diagnostic Substances)
ALEC Alector, Inc.
0.413
0.299 0.92× similar Biological Products, (No Diagnostic Substances)
BNTC Benitec Biopharma Inc.
0.411
0.184 0.63× 37% calmer Pharmaceutical Preparations
LXEO Lexeo Therapeutics, Inc.
0.402
0.261 0.78× 22% calmer Biological Products, (No Diagnostic Substances)
RCKT Rocket Pharmaceuticals, Inc.
0.394
0.298 0.75× 25% calmer Pharmaceutical Preparations
EDIT Editas Medicine, Inc.
0.393
0.288 0.90× similar Biological Products, (No Diagnostic Substances)
MLYS Mineralys Therapeutics, Inc.
0.384
0.229 0.68× 32% calmer Pharmaceutical Preparations
CMTG Claros Mortgage Trust, Inc.
0.382
0.265 0.99× similar Real Estate
CRCT Cricut, Inc.
0.382
0.200 0.71× 29% calmer Special Industry Machinery, Nec
BEAM Beam Therapeutics Inc.
0.375
0.365 0.79× 21% calmer Biological Products, (No Diagnostic Substances)
DTIL Precision BioSciences, Inc.
0.374
0.223 0.81× 19% calmer Biological Products, (No Diagnostic Substances)
DYN Dyne Therapeutics, Inc.
0.372
0.222 0.70× 30% calmer Pharmaceutical Preparations
IMMX Immix Biopharma, Inc.
0.369
0.121 0.92× similar Pharmaceutical Preparations
VYGR Voyager Therapeutics, Inc.
0.355
0.284 0.67× 33% calmer Biological Products, (No Diagnostic Substances)
ARVN Arvinas, Inc.
0.352
0.244 0.62× 38% calmer Pharmaceutical Preparations
XNCR Xencor, Inc.
0.349
0.294 0.72× 28% calmer Pharmaceutical Preparations
MGTX MeiraGTx Holdings plc
0.348
0.254 0.64× 36% calmer Biological Products, (No Diagnostic Substances)
ASMB Assembly Biosciences, Inc.
0.343
0.216 0.65× 35% calmer Pharmaceutical Preparations
RLAY Relay Therapeutics, Inc.
0.338
0.292 0.72× 29% calmer Biological Products, (No Diagnostic Substances)
VKTX Viking Therapeutics, Inc.
0.337
0.227 0.76× 24% calmer Pharmaceutical Preparations
ALLO Allogene Therapeutics, Inc.
0.336
0.319 0.91× similar Biological Products, (No Diagnostic Substances)
OPRT Oportun Financial Corporation
0.333
0.162 0.77× 23% calmer Finance Services
VRDN Viridian Therapeutics, Inc.
0.332
0.303 0.79× 21% calmer Pharmaceutical Preparations
VIR Vir Biotechnology, Inc.
0.332
0.263 0.72× 28% calmer Biological Products, (No Diagnostic Substances)

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.