What Moves Like RYTM

Rhythm Pharmaceuticals, Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track RYTM most closely over the past year, filtered to risk comparable with RYTM's own.

Closest match

XBI State Street SPDR S&P Biotech ETF — 0.579 correlation over the past year, and 40% calmer than RYTM.

About RYTM

Annualised volatility 46.3%
Beta vs SPY 0.97
Market correlation 0.269
Traded per day $61.1M

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Revenue $189.8M
Operating income -$192.0M
Net income -$196.5M
Diluted EPS $-3.11
Total assets $442.3M
Total liabilities $204.7M
Shareholders' equity $122.9M
Cash & equivalents $62.1M
Shares outstanding 68.4M
252 sessions to 2026-09-10 · RYTM volatility 46.3% annualised · $61.1M a day
Ticker 1-year correlation 3-year Volatility vs RYTM Risk What it is
XBI State Street SPDR S&P Biotech ETF
0.579
0.522 0.60× 40% calmer Fund
SBIO ALPS Medical Breakthroughs ETF
0.571
0.539 0.67× 33% calmer Fund
SRRK Scholar Rock Holding Corporation
0.434
0.231 1.30× 30% choppier Biological Products, (No Diagnostic Substances)
VIR Vir Biotechnology, Inc.
0.422
0.310 1.41× 41% choppier Biological Products, (No Diagnostic Substances)
ACAD ACADIA Pharmaceuticals Inc.
0.411
0.250 0.82× 18% calmer Pharmaceutical Preparations
GMAB Genmab A/S
0.409
0.249 0.72× 28% calmer Pharmaceutical Preparations
SUPN Supernus Pharmaceuticals, Inc.
0.406
0.221 0.77× 23% calmer Pharmaceutical Preparations
PCVX Vaxcyte, Inc.
0.397
0.291 0.99× similar Biological Products, (No Diagnostic Substances)
ALKS Alkermes plc
0.389
0.276 0.87× 13% calmer Pharmaceutical Preparations
GERN Geron Corporation
0.381
0.198 1.39× 39% choppier Pharmaceutical Preparations
IDYA IDEAYA Biosciences, Inc.
0.379
0.375 0.99× similar Pharmaceutical Preparations
SVRA Savara, Inc.
0.378
0.283 1.16× 16% choppier Pharmaceutical Preparations
MIRM Mirum Pharmaceuticals, Inc.
0.376
0.289 0.98× similar Pharmaceutical Preparations
ARKG ARK Genomic Revolution ETF
0.372
0.396 0.97× similar Fund
DNLI Denali Therapeutics Inc.
0.363
0.377 1.22× 22% choppier Biological Products, (No Diagnostic Substances)
AURA Aura Biosciences, Inc.
0.360
0.304 1.24× 24% choppier Biological Products, (No Diagnostic Substances)
SPRY ARS Pharmaceuticals, Inc.
0.355
0.243 1.58× 58% choppier Pharmaceutical Preparations
XNCR Xencor, Inc.
0.355
0.330 1.45× 45% choppier Pharmaceutical Preparations
CLDX Celldex Therapeutics, Inc.
0.352
0.323 1.09× similar In Vitro & In Vivo Diagnostic Substances
GRFS Grifols, S.A.
0.350
0.214 0.69× 31% calmer Pharmaceutical Preparations
RCUS Arcus Biosciences, Inc.
0.347
0.337 1.33× 33% choppier Pharmaceutical Preparations
BBIO BridgeBio Pharma, Inc.
0.347
0.353 1.01× similar Pharmaceutical Preparations
ABUS Arbutus Biopharma Corporation
0.341
0.267 1.01× similar Pharmaceutical Preparations
EQH Equitable Holdings, Inc.
0.337
0.260 0.72× 28% calmer Insurance Agents, Brokers & Service
CGON CG Oncology, Inc.
0.336
1.22× 22% choppier Biological Products, (No Diagnostic Substances)

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.