What Moves Like ACAD

ACADIA Pharmaceuticals Inc. Pharmaceutical Preparations · Nasdaq

The tradable tickers whose daily moves track ACAD most closely over the past year, filtered to risk comparable with ACAD's own.

Closest match

XBI State Street SPDR S&P Biotech ETF — 0.563 correlation over the past year, and 26% calmer than ACAD.

About ACAD

Annualised volatility 37.9%
Beta vs SPY 0.85
Market correlation 0.288
Traded per day $34.2M

As filed with the SEC twelve months to 2025-12-31 · balance sheet 2026-03-31

Revenue $1.07B
Operating income $104.8M
Net income $391.0M
Diluted EPS $2.30
Total assets $1.61B
Total liabilities $357.2M
Shareholders' equity $1.25B
Cash & equivalents $282.2M
Shares outstanding 171.1M
252 sessions to 2026-09-10 · ACAD volatility 37.9% annualised · $34.2M a day
Ticker 1-year correlation 3-year Volatility vs ACAD Risk What it is
XBI State Street SPDR S&P Biotech ETF
0.563
0.481 0.74× 26% calmer Fund
SBIO ALPS Medical Breakthroughs ETF
0.545
0.478 0.82× 18% calmer Fund
XPH State Street SPDR S&P Pharmaceuticals ETF
0.510
0.438 0.61× 39% calmer Fund
KRYS Krystal Biotech, Inc.
0.427
0.290 1.03× similar Biological Products, (No Diagnostic Substances)
CLDX Celldex Therapeutics, Inc.
0.426
0.326 1.33× 33% choppier In Vitro & In Vivo Diagnostic Substances
IDYA IDEAYA Biosciences, Inc.
0.424
0.275 1.21× 21% choppier Pharmaceutical Preparations
ABUS Arbutus Biopharma Corporation
0.420
0.298 1.24× 24% choppier Pharmaceutical Preparations
RYTM Rhythm Pharmaceuticals, Inc.
0.411
0.250 1.22× 22% choppier Pharmaceutical Preparations
DNLI Denali Therapeutics Inc.
0.409
0.371 1.49× 49% choppier Biological Products, (No Diagnostic Substances)
ARKG ARK Genomic Revolution ETF
0.402
0.413 1.18× 18% choppier Fund
NTRA Natera, Inc.
0.398
0.255 1.26× 26% choppier Services-Medical Laboratories
VRTX Vertex Pharmaceuticals Incorporated
0.391
0.349 0.76× 24% calmer Pharmaceutical Preparations
HRMY Harmony Biosciences Holdings, Inc.
0.385
0.249 1.17× 17% choppier Pharmaceutical Preparations
EXEL Exelixis, Inc.
0.384
0.158 0.98× similar Biological Products, (No Diagnostic Substances)
XHE State Street SPDR S&P Health Care Equipment ETF
0.380
0.365 0.60× 40% calmer Fund
MGTX MeiraGTx Holdings plc
0.379
0.301 1.58× 58% choppier Biological Products, (No Diagnostic Substances)
KROS Keros Therapeutics, Inc.
0.379
0.208 1.32× 32% choppier Pharmaceutical Preparations
IWC iShares Microcap ETF
0.375
0.399 0.63× 37% calmer Fund
AMGN Amgen Inc.
0.371
0.283 0.78× 22% calmer Biological Products, (No Diagnostic Substances)
INCY Incyte Corporation
0.371
0.295 0.88× 12% calmer Services-Commercial Physical & Biological Research
SRRK Scholar Rock Holding Corporation
0.364
0.192 1.59× 59% choppier Biological Products, (No Diagnostic Substances)
STOK Stoke Therapeutics, Inc.
0.363
0.270 1.55× 55% choppier Pharmaceutical Preparations
BLCO Bausch + Lomb Corporation
0.361
0.238 0.77× 23% calmer Ophthalmic Goods
KURA Kura Oncology, Inc.
0.359
0.225 1.60× 60% choppier Pharmaceutical Preparations
MIRM Mirum Pharmaceuticals, Inc.
0.358
0.212 1.20× 20% choppier Pharmaceutical Preparations

Showing 25 of 30 tickers that qualified. Correlation is of daily returns; 1.000 would mean moving in lockstep, 0.000 no relationship at all.

What this is for

Three questions, one number behind all of them.

How to read the two correlation columns

The one-year figure is what the relationship looks like now. The three-year figure is what it has looked like over a longer stretch. Comparing them is the point: when they agree, the relationship is structural and likely to hold. When the one-year number is far below the three-year one, something has changed — a shift in business mix, an index reconstitution, a sector that has stopped moving together — and the recent figure is the one to trust less, not more.

Correlation measures whether two things move together, not whether they move by the same amount. That is why the volatility column is there. Two tickers can correlate at 0.99 while one swings half again as hard, and swapping one for the other would quietly change how much risk you are carrying.

What was deliberately left out

Ranking purely by correlation produces answers that are mathematically perfect and practically useless. The closest matches to AAPL by raw correlation are leveraged AAPL funds at 0.999 — correct, and not replacements for anything. Four filters run before a ticker is allowed to appear:

Where all of that leaves a ticker with no close match, the page says so. A stock with no substitute is a real and useful finding, and inventing a loose one to fill the table would be worse than an empty answer.

Limits, stated up front

Where the numbers come from

Correlations are computed in-house from a daily price history and rebuilt every night. What gets published is the derived statistic — a correlation coefficient, a volatility ratio, an observation count — and nothing from which a price or return series could be reconstructed. The rest of the Markets section is on the Markets overview, including futures positioning extremes and SEC Form 4 insider transactions.